Enhanced in vitro synthesis of igm rheumatoid factor in rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Control of Rheumatoid Arthritis in Developing Countries
بیماری روماتیسم قلبی یکی از شایعترین علل مرگ و میر ناشی از بیماریهای قلبی و عروقی در کشورهای در حال توسعه می باشد. براساس بررسیهای انجام شده، میزان شیوع بیماری در جامعه و مدارس از ۱ الی ۲۲ در هر هزار نفر کودک می باشد. تخمین زده میشود که تعداد مبتلایان به بیماریهای مزمن روماتیسم قلبی در کشورهای در حال توسعه ۳۰ میلیون و در کشورهای صنعتی ۱ / ۵ میلیون باشد. بسیاری از موارد مرگ و میر ناشی از این بیم...
متن کاملComparative Measurement of Rheumatoid Factor in Serum and Synovial Fluid of Rheumatoid Arthritis Patients by ELISA and Latex-Agglutination Test
Rheumatoid factors (RF) are autoantibodies with specificity for the Fc portion of human IgG. Production of RF is a characteristic feature of rheumatoid arthritis (RA) and is detectable in high titer in about 90% of these patients. In this study, we measured total IgM, IgA, IgMRF and IgARF in serum and synovial fluid of 45 RA patients by ELISA and the results were compared with those obtained b...
متن کاملHLA studies in IgM rheumatoid-factor-positive arthritis of childhood.
The clinical course of children with IgM rheumatoid-factor-positive chronic arthritis closely resembles that of seropositive rheumatoid disease in adults. The frequency of HLA DR4 is known to be increased in adults with seropositive rheumatoid arthritis, but the first major report on childhood arthritis did not suggest a correlation, though only 8 seropositive cases were included. Fifty-two chi...
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High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...
متن کاملANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODI ES IN RHEUMATOID ARTHRITIS
Antineutrophil cytoplasmic autoantibodies (ANCA) were detected in patients with autoimmune and vascular diseases such as Wegener's granulomatosis, polyarteritis nodosa and systemic lupus erythematosus. Indirect immunofluorescence (IIF) technique was employed to detect these autoantibodies. By this method, two general patterns of ANCA were seen: a cytoplasmic (cANCA) and a perinuclear form ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1980
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780230904